Product microbiological testing

Each component used in baby wipes must pass a series of quality check points during the manufacturing process. The plastic packaging must be free from mold defects that could cause leakage or improper closure. The non-woven fabric must be uniformly formed and must meet specific tear-strength requirements. Furthermore, prior to manufacture, the cleansing solution must be thoroughly tested. Development chemists evaluate the product to ensure that it is shelf stable and will not undergo any undesirable chemical reactions. They must also test the formula to ensure that it satisfies the requirements for mildness. The most reliable method used to test mildness is known as the Human Repeat Insult Patch Test (HRIPT). In this test an ingredient, or series of ingredients, is applied to human volunteers (usually on the inside of the forearm). The area is then occluded with a patch material and the spot is evaluated by dermatologists or clinicians after a specified time. Any redness or irritation is assigned numerical value and the scores of all the panelists are averaged. A low average score, such as 0 or 1, indicates that the product is essentially non-irritating.

Before ingredients are added to the batch tank, they are assayed to ensure they conform to all relevant specifications. During manufacture, each ingredient is check weighed before it is added to the batch. Then final batch is tested again for basic specifications such as pH, viscosity, and microbial content.